Hmm… even though he didn’t answer the question, I’m inclined to believe the director would like to see Emma Thompson back in her role after those comments. It would be a “shame,” because she was amazing in the role. As we learn at the end of the flick, the Baroness is, in fact, Cruella’s real mother, but a mother who wanted her child to be killed shortly after her birth. When she had the chance at the end of the film, the Baroness attempted to murder her daughter once and for all, but she was not successful. The movie ends with the Baroness being sent off to jail for killing Estella, Cruella’s alter ego.
Article source: https://www.cinemablend.com/news/2574075/cruella-director-sequel-hopes-emma-thompson-possible-return-emma-stone