Perhaps in this pair’s quest of multiversal multitudes, not only would Peter Parker’s existence come into play, but also the entire Spider-Verse. This would lay down groundwork for potential cross overs with Venom, Morbius, and even the entire Spider Fam from Spider-Man: Into The Spider-Verse. The cherry on the sundae would be that if Sony can cast a candidate pretty damned quick, they could even use this film to tease the eventual arrival of the newly announced Madame Web, formally introducing Cassandra Webb and Peter Parker.
Article source: https://www.cinemablend.com/news/2481171/tom-hollands-spider-man-will-get-another-marvel-appearance-but-which-movies