In Long Shot, Rogen plays a journalist who recently quit his gig due to a corporation taking over. He eventually catches the eye of a presidential hopeful played by Charlize Theron, who was his babysitter as a kid. He starts speechwriting for her and they develop a bond that turns into an unlikely romantic entanglement. And yes, it seems Seth Rogen was stoned while filming it, which is pretty fitting for the character, Fred Flarsky, he plays in the film.
Article source: https://www.cinemablend.com/news/2471073/yes-seth-rogen-is-always-high-when-filming-movies